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Neuroanatomy of Fragile X Syndrome:The Temporal Lobe Neurol 44:1317-1324, Reiss,A.L.,et al, 1994 See this aricle in Pubmed Article Abstract Subjects with the fragile X mutation showed an age-related increase in volume of the hippocampus and an age-related de4crease in volume of the superior temporal gyrus.Along with the findings of previous imaging studies of fragile X subjects,the results of the present investigation are consistent with studies showing a nonrandom distribution of expression of the FMR-1 gene in the developing brain,with increased expression in the cerebellum,hippocampus,and specific cortical regions.The results also suggest involvement of temporal lobe regions in the behavioral and cognitive abnormalities associated with fragile X syndrome.

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(click to filter results - removes previous filter) anatomy of fragile-X syndrome hippocampus MRI MRI,abnormal MRI,volumetry temporal lobe temporal lobe,anatomy and physiology

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